ANTIBIOTICS VS EARLY APPENDECTOMY IN UNCOMPLICATED ACUTE APPENDICITIS
Keywords:
Appendicitis. Appendectomy. Anti-Bacterial Agents. Nonoperative Management. Quality of LifeAbstract
DOI: https://doi.org/10.46296/yc.v10i18.0878
Abstract
A critical topic review was conducted on antibiotic management versus early appendectomy in uncomplicated acute appendicitis. Recent biomedical literature was examined, prioritizing randomized trials, meta-analyses, comparative cohorts, and guidelines. The evidence showed that antibiotics avoided immediate surgery in a substantial proportion of patients and did not consistently increase early major complications in well-selected cases. However, this strategy carried a relevant cumulative recurrence risk during follow-up, particularly when an appendicolith was present. Surgery remained the most definitive treatment, whereas conservative management offered lower initial invasiveness, faster recovery, and lower costs. Both strategies were considered valid, but patient selection, imaging confirmation, and shared decision-making were essential to determine the most appropriate therapeutic approach.
Keywords: Appendicitis. Appendectomy. Anti-Bacterial Agents. Nonoperative Management. Quality of Life.
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