UNSTABLE PELVIC FRACTURE: INITIAL MANAGEMENT AND HEMORRHAGE CONTROL

Authors

Keywords:

pelvic fractures; hemorrhage; hemorrhagic shock; therapeutic embolization; preperitoneal packing; REBOA; damage control

Abstract

DOI: https://doi.org/10.46296/yc.v10i19.0988

Abstract

Introduction: Unstable pelvic ring fractures associated with hemorrhagic shock constitute a time-critical emergency. Mortality is linked not only to the anatomical severity of the injury but also to the speed with which mechanical and hemostatic control is achieved. Controversies persist regarding the optimal sequence of preperitoneal pelvic packing (PPP), angioembolization (AE), and resuscitative endovascular balloon occlusion of the aorta (REBOA). Objective: To synthesize the evidence available up to April 30, 2026, regarding initial management and hemorrhage control strategies in adults with unstable pelvic fractures and hemodynamic instability, prioritizing studies with retrievable full text. Methods: A systematic review guided by PRISMA 2020. Reproducible search strategies were designed for PubMed/MEDLINE, Google Scholar, SciELO, and Scopus, using terms related to pelvic fracture, hemodynamic instability, hemorrhage, pelvic binder, preperitoneal packing, angioembolization, and REBOA. Primary studies involving adults, published between 2000 and April 30, 2026, with retrievable full text and clinical outcomes regarding hemorrhage control, were included. Due to the heterogeneity of populations, definitions, and therapeutic sequences, as well as the overlap of national cohorts, a structured narrative synthesis was performed instead of a *de novo* meta-analysis. Results: Fifteen primary studies were included. Circumferential pelvic stabilization is an immediate measure that can be implemented quickly, although recent studies show frequent placement errors. PPP provides rapid control of predominantly venous/osseous bleeding and is consistently associated with reduced transfusion requirements; between 9% and 31% of patients in some series required secondary AE. AE is the definitive treatment for arterial bleeding, and contemporary studies emphasize that its benefit depends on rapid access. Adjusted comparisons between PPP and AE do not show uniform causal superiority; The choice is strongly conditioned by the severity and the context. REBOA can transiently raise central pressure, but the evidence remains observational, inconsistent, and subject to confounding by indication; it should be considered a rescue bridge rather than a definitive therapy. Conclusions: Evidence supports a physiological and resource-dependent algorithm: damage-control resuscitation, a correctly placed binder, rapid exclusion of other sources of hemorrhage, and prompt access to the most readily available definitive treatment. In centers with immediate endovascular capabilities, arterial embolization (AE) is appropriate when arterial bleeding is suspected; in cases of profound shock, the need for laparotomy, or delays in endovascular intervention, pelvic packing (PPP) combined with mechanical stabilization offers rapid control and can be supplemented by AE. There is no high-certainty evidence to justify a "one-size-fits-all" strategy for all patients.

Keywords: pelvic fractures; hemorrhage; hemorrhagic shock; therapeutic embolization; preperitoneal packing; REBOA; damage control.

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References

Coccolini F, Stahel PF, Montori G, et al. Pelvic trauma: WSES classification and guidelines. World J Emerg Surg. 2017;12:5. doi:10.1186/s13017-017-0117-6.

Cullinane DC, Schiller HJ, Zielinski MD, et al. Eastern Association for the Surgery of Trauma practice management guidelines for hemorrhage in pelvic fracture. J Trauma. 2011;71(6):1850-1868.

Marmor M, El Naga AN, Barker J, Matz J, Stergiadou S, Miclau T. Management of pelvic ring injury patients with hemodynamic instability. Front Surg. 2020;7:588845. doi:10.3389/fsurg.2020.588845.

Osborn PM, Smith WR, Moore EE, et al. Direct retroperitoneal pelvic packing versus pelvic angiography: a comparison of two management protocols for haemodynamically unstable pelvic fractures. Injury. 2009;40(1):54-60. doi:10.1016/j.injury.2008.08.038.

Jang JY, Shim H, Jung PY, Kim S, Bae KS. Preperitoneal pelvic packing in patients with hemodynamic instability due to severe pelvic fracture: early experience in a Korean trauma center. Scand J Trauma Resusc Emerg Med. 2016;24:3. doi:10.1186/s13049-016-0196-5.

Burlew CC, Moore EE, Stahel PF, et al. Preperitoneal pelvic packing reduces mortality in patients with life-threatening hemorrhage due to unstable pelvic fractures. J Trauma Acute Care Surg. 2017;82(2):233-242. doi:10.1097/TA.0000000000001324.

Shim H, Jang JY, Kim JW, et al. Effectiveness and postoperative wound infection of preperitoneal pelvic packing in patients with hemodynamic instability caused by pelvic fracture. PLoS One. 2018;13(11):e0206991. doi:10.1371/journal.pone.0206991.

Lustenberger T, Störmann P, Eichler K, Nau C, Janko M, Marzi I. Secondary angio-embolization after emergent pelvic stabilization and pelvic packing is a safe option for patients with persistent hemorrhage from unstable pelvic ring injuries. Front Surg. 2020;7:601140. doi:10.3389/fsurg.2020.601140.

Wang Q, et al. The effect of preperitoneal pelvic packing for hemodynamically unstable patients with pelvic fractures. Eur J Trauma Emerg Surg. 2021. PMID:33627295.

Werner NL, Moore EE, Hoehn M, et al. Inflate and pack! Pelvic packing combined with REBOA deployment prevents hemorrhage related deaths in unstable pelvic fractures. Injury. 2022;53(10):3365-3370. doi:10.1016/j.injury.2022.07.025.

Aoki M, Matsushima K, Matsumoto S. Angioembolization versus preperitoneal packing for severe pelvic fractures: a propensity matched analysis. Am J Surg. 2023;225(2):408-413. doi:10.1016/j.amjsurg.2022.09.003.

Anand T, et al. Association between hemorrhage control interventions and mortality in US trauma patients with hemodynamically unstable pelvic fractures. JAMA Surg. 2023;158(1):63-71. PMID:36449300.

Choi K, Keum MA, Choi B, et al. Effectiveness and safety of bilateral internal iliac artery ligation with pre-peritoneal pelvic packing for life-threatening pelvic trauma. Injury. 2023;54(2):598-603. doi:10.1016/j.injury.2022.11.003.

Gong SC, Park JE, et al. Preperitoneal pelvic packing versus angioembolization for patients with hemodynamically unstable pelvic fractures with pelvic bleeding: a single-centered retrospective study. Healthcare (Basel). 2023;11(12):1784. doi:10.3390/healthcare11121784.

DuanMu B, Du X, Sun J, et al. Timely angiography and embolization is effective emergency treatment for severe post-traumatic pelvic fractures. Sci Rep. 2025;15:12530. doi:10.1038/s41598-025-88322-8.

Page MJ, McKenzie JE, Bossuyt PM, et al. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ. 2021;372:n71. doi:10.1136/bmj.n71.

Sterne JAC, Hernán MA, Reeves BC, et al. ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions. BMJ. 2016;355:i4919. doi:10.1136/bmj.i4919.

Timon C, Kilkenny C, O'Sullivan K, Bracken A, Fournier J, O'Daly B. An assessment of pelvic binder placement on patients referred to the Irish national centre for pelvic and acetabular fractures. Ir J Med Sci. 2026;195(2):769-772. doi:10.1007/s11845-025-04262-2.

Harfouche MN, Sult L, Sciarretta JD, et al. To pack or plug: American Association for the Surgery of Trauma multicenter evaluation of hemorrhage control interventions in pelvic fracture management. J Trauma Acute Care Surg. 2026;100(3):398-404. doi:10.1097/TA.0000000000004856.

Lee SH, Kim JT, Choi S, et al. Outcomes of emergency department and operating room preperitoneal pelvic packing in hemodynamically unstable severe pelvic fractures: a retrospective risk-adjusted observational study. World J Emerg Surg. 2026;21:35. doi:10.1186/s13017-026-00695-x.

McDonogh JM, Lewis DP, Tarrant SM, Balogh ZJ. Preperitoneal packing versus angioembolization for the initial management of hemodynamically unstable pelvic fracture: a systematic review and meta-analysis. J Trauma Acute Care Surg. 2022;92(5):931-939. doi:10.1097/TA.0000000000003528.

Wendt K, et al. Arterial angioembolisation versus pre-peritoneal pelvic packing in haemodynamically unstable patients with complex pelvic fractures: a meta-analysis. Eur J Trauma Emerg Surg. 2024;50(4):1295-1304. doi:10.1007/s00068-023-02389-4.

Martinez M, et al. Preperitoneal packing versus angioembolization in pelvic fracture-related hemorrhage: systematic review and meta-analysis. Am Surg. 2024. PMID:37970830. Note: existe una Expression of Concern posterior; interpretar con cautela.

Houdane A, et al. Assessing the role of resuscitative endovascular balloon occlusion of the aorta in hemodynamically unstable pelvic fractures: a systematic review and meta-analysis. Eur J Trauma Emerg Surg. 2026. PMID:41697361.

Campbell M, McKenzie JE, Sowden A, et al. Synthesis without meta-analysis (SWiM) in systematic reviews: reporting guideline. BMJ. 2020;368:l6890. doi:10.1136/bmj.l6890.

Published

2026-08-28

How to Cite

Jiménez-Jiménez, J. A., Ortega-Riofrio, C. M., Solórzano-Castillo, F. D., & Pichasaca-Guamán, L. F. (2026). UNSTABLE PELVIC FRACTURE: INITIAL MANAGEMENT AND HEMORRHAGE CONTROL. REVISTA CIENTÍFICA MULTIDISCIPLINARIA ARBITRADA YACHASUN - ISSN: 2697-3456, 10(19), 1237–1255. Retrieved from https://editorialibkn.com/index.php/Yachasun/article/view/1069